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6.1.3 Default profile

What about the default profile that Guix keeps in ~/.guix-profile?

You can assign it the role you want. Typically you would install the manifest of the packages you want to use all the time.

Alternatively, you could keep it “manifest-less” for throw-away packages that you would just use for a couple of days. This way makes it convenient to run

guix install package-foo
guix upgrade package-bar

without having to specify the path to a profile.